Bacopa
monnieri | ||||||
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Botanical Name :Bacopa
monnieri
Description of
Bacopa monnieri:
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Principal Constituents: The herb contains the alkaloids brahmine, herpestine, and a mixture of three bases. It also contains the saponins, monnierin ; hersaponin, bacoside A and bacoside B. Other constituents present in the plant are D-mannitol, betulic acid, ß- sitosterol, stigmasterol and its esters, heptacosane, octacosane, nonacosane, triacontane, hentriacontane, dotriacontane, nicotine, 3-formyl-4-hydroxy-2H-pyran, luteolin and its 7-glucoside. The presence of a-alamine, aspartic acid, glutamic acid and serine is also reported Pharmacology: The saponin, hersaponin, is reported to possess cardiotonic, sedative and spasmodic properties. It produced a mild inhibitory effect on the respiration of rat brain tissue which was partially reduced by LSD-25 and potentiated by 5-HT. It was also found, as in the case of reserpine, to deplete nor-adrenaline and 5-HT content of the rat brain. An alcoholic extract of the plant, in a dose of 50mg/kg, produced a tranquilizing effect on albino rats and dogs but the action was weaker than that produced by chlorpromazine. An ethanolic extract (50%) of the plant exhibited anticancer activity against the Walker carcinosarcoma 256 in rats. The administration of an aqueous suspension of an alcoholic extract (40mg/kg, p.o.) for three or more days is reported to improve the performance of rats in various learning situations.
Medicinal Uses: Herbal Extract packing:
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